A more natural phrasing in 21st-century English would be: "He who does not love wine, wife, and song will be a fool his whole life long."

A print published by Kimmel and Voigt in New York, 1873.

In addition to its obvious meaning (and a reference to Strauss' "Wine Wife and Song Waltz"), this is also a vigorous assertion of the cultural values of German-American immigrants in the face of "Temperance" and "Maine Law" campaigners (i.e. alcohol prohibitionists), and other reformers who judged immigrants from a "native American" and/or English-speaking Protestant fundamentalist point of view.

For an opposing point of view (women who saw alcohol as a major aggravating factor in men's mistreatment of their families, and its prohibition as a highly-positive social reform), see Image:Womans-Holy-War.jpg.