2C-I-FLY

2C-I-FLY
臨床資料
藥物類別	Serotonergic psychedelic; Hallucinogen
ATC碼	未分配;
识别信息
	IUPAC命名法 2-(4-iodo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-8-yl)ethanamine; ;
CAS号	1354633-88-7
PubChem CID	166922865;
化学信息
化学式	C12H14INO2
摩尔质量	331.15 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES C1COC2=C(C3=C(C(=C21)CCN)OCC3)I;
	InChI InChI=1S/C12H14INO2/c13-10-9-3-6-15-11(9)7(1-4-14)8-2-5-16-12(8)10/h1-6,14H2; Key:SDULYHWSVCNNAO-UHFFFAOYSA-N;

2C-I-FLY（化学名：2-(4-碘-2,3,6,7-四氢呋喃并[2,3-f][1]苯并呋喃-8-基)乙胺^[1]）是一种具有苯乙胺结构的迷幻药物，是一种单胺氧化酶A抑制剂（IC₅₀ = 13 μM）。^[2]它可引起啮齿动物的头部抽搐反应，这符合迷幻药作用的行为学指标。^[3]

参考文献

^ Lea Wagmann; et al. Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings. Drug Testing and Analysis, 2019. 11 (10): 1507-1521. doi:10.1002/dta.2675.
^ Wagmann L, Brandt SD, Stratford A, Maurer HH, Meyer MR. Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases (PDF). Drug Testing and Analysis. February 2019, 11 (2): 318–324. PMID 30188017. doi:10.1002/dta.2494.
^ Halberstadt AL, Chatha M, Stratford A, Grill M, Brandt SD. Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs. Neuropharmacology. January 2019, 144: 368–376. PMC 6863604 . PMID 30385253. doi:10.1016/j.neuropharm.2018.10.037.