2-氰基-2-(2-吲哚啉酮-3-亚基)乙酸乙酯

2-氰基-2-(2-吲哚啉酮-3-亚基)乙酸乙酯
识别
CAS号	14003-18-0（Z） ?; 14003-19-1; 59225-18-2
PubChem	260547
SMILES	O=C(OCC)C(C#N)=C1C(NC2=C1C=CC=C2)=O;
性质
化学式	C13H10N2O3
摩尔质量	242.23 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

2-氰基-2-(2-吲哚啉酮-3-亚基)乙酸乙酯是一种有机化合物，化学式为C₁₃H₁₀N₂O₃。它可由靛红和氰乙酸乙酯在乙醇中加热反应制得。^[1]它和2-(氰基乙酰氨基)苯甲酸甲酯反应，可以得到6'-氨基-3'-氰基-1'-(2-(甲氧羰基)苯基)-2,2'-二氧代-2',3'-二氢-1'H-螺[吲哚啉-3,4'-吡啶]-5'-甲酸乙酯。^[2]

参考文献

^ Najafi, M., Marandi, G. Synthesis of novel organophosphorus compounds via reaction of substituted 2-oxoindoline-3-ylidene with acetylenic diesters and triphenylphosphine or triphenyl phosphite. Sci Rep 14, 6314 (2024). doi:10.1038/s41598-024-56774-z
^ Ammar, Yossry A.; et al. "Cyanoacetanilide intermediates in heterocyclic synthesis. Part 7: preparation of some spiro[indoline-3,4′-pyridine] and chromeno[3,4-c]pyridine derivatives" Heterocyclic Communications, vol. 19, no. 3, 2013, pp. 195-200. doi:10.1515/hc-2013-0032

[1] Najafi, M., Marandi, G. Synthesis of novel organophosphorus compounds via reaction of substituted 2-oxoindoline-3-ylidene with acetylenic diesters and triphenylphosphine or triphenyl phosphite. Sci Rep 14, 6314 (2024). doi:10.1038/s41598-024-56774-z

[2] Ammar, Yossry A.; et al. "Cyanoacetanilide intermediates in heterocyclic synthesis. Part 7: preparation of some spiro[indoline-3,4′-pyridine] and chromeno[3,4-c]pyridine derivatives" Heterocyclic Communications, vol. 19, no. 3, 2013, pp. 195-200. doi:10.1515/hc-2013-0032

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