IHCH-8134

IHCH-8134
臨床資料
藥物類別	Serotonin 5-HT2A receptor agonist
识别信息
	IUPAC命名法 (6bR,10aS)-8-(3-(2-methoxyphenyl)propyl)-1,2,6b,7,8,9,10,10a-octahydro-[1,4]oxazino[2,3,4-hi]pyrido[4,3-b]indole; ;
PubChem CID	172549469;
化学信息
化学式	C23H28N2O2
摩尔质量	364.49 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES [H][C@@]12[C@@](CCN(CCCC3=CC=CC=C3OC)C2)([H])N4CCOC5=C4C1=CC=C5;
	InChI InChI=1S/C23H28N2O2/c1-26-21-9-3-2-6-17(21)7-5-12-24-13-11-20-19(16-24)18-8-4-10-22-23(18)25(20)14-15-27-22/h2-4,6,8-10,19-20H,5,7,11-16H2,1H3/t19-,20-/m0/s1; Key:XIZOEKLHAJIDMD-PMACEKPBSA-N;

IHCH-8134是一种含氮有机化合物，分子式C
23H
28N
2O
2，带有一个含氮四环结构，可作为血清素 5-HT_2A受体的激动剂。^[1]^[2]^[3]

参考文献

^ US 6552017,Robichaud AJ, Lee T, Deng W, Mitchell IS, Yang MG, Haydar S, Chen W, Mc Clung CD, Calvello EJ, Zawrotny DM,「Substituted heterocycle fused gamma-carbolines.」,发行于22 April 2003
^ US 9315504,Tomesch JC, Li P, Yao W, Zhang Q, Beard JD, Thompson AS, Cheng H, Wennogle LP,「Preparation of 4-((6BR,10AS)-3-methyl-2,3,6B,9,10, 10A-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalin-8-(7H)-yl)-1-(4-fluorophenyl)-1-butanone or a pharmaceutically acceptable salt thereof」,发行于19 April 2016
^ Cao D, Yu J, Wang H, Luo Z, Liu X, He L, Qi J, Fan L, Tang L, Chen Z, Li J, Cheng J, Wang S. Structure-based discovery of nonhallucinogenic psychedelic analogs. Science (New York, N.Y.). January 2022, 375 (6579): 403–411. Bibcode:2022Sci...375..403C. PMID 35084960. S2CID 246360313. doi:10.1126/science.abl8615.