TAX1BP1
外观
TAX1BP1(Tax1 binding protein 1,“Tax1结合蛋白1”)也称为CALCOCO3(Calcium-binding and coiled-coil domain-containing protein 3,“钙结合和卷曲螺旋区蛋白3”)是人类基因 TAX1BP1 编码的蛋白质[5],其名称来源于能和人類嗜T淋巴球病毒一型(HTLV-1)的蛋白Tax1结合[5]。
蛋白质的相互作用
[编辑]TAX1BP1蛋白与下列蛋白質进行互作:A20[6]和TRAF6[7],在与A20或TRAF6结合后抑制NF-κB转录因子激活。
参考文献
[编辑]- ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000106052 – Ensembl, May 2017
- ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000004535 – Ensembl, 2017年5月
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ 5.0 5.1 Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1.
- ^ De Valck D, Jin DY, Heyninck K, Van de Craen M, Contreras R, Fiers W, Jeang KT, Beyaert R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. July 1999, 18 (29): 4182–90. PMID 10435631. doi:10.1038/sj.onc.1202787
.
- ^ Ling L, Goeddel DV. T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. August 2000, 97 (17): 9567–72. Bibcode:2000PNAS...97.9567L. PMC 16905
. PMID 10920205. doi:10.1073/pnas.170279097
.