CDKN2C

CDKN2C
已知的結構
PDB	直系同源搜尋：PDBe RCSB
PDBID列表
	1BU9、1G3N、1IHB、1MX2、1MX4、1MX6
標識符
代號	CDKN2C
擴展標識	OMIM：603369；MGI：105388；HomoloGene：966；GeneCards：CDKN2C；OMA：CDKN2C - orthologs
基因位置（人類）
染色體	1號染色體
終止	50,974,634 bp
基因位置（小鼠）
染色體	小鼠4號染色體
終止	109,524,386 bp
RNA表達模式
	Top expressed in
	ventricular zone; ; tibial arteries; ; abdominal fat; ; subcutaneous adipose tissue;
	Top expressed in
	lactiferous gland; ; tibiofemoral joint; ; subcutaneous adipose tissue; ; epithelium of lens; ; fetal liver hematopoietic progenitor cell;
	查閱更多表達數據
	; ;
	查閱更多表達數據
基因本體
分子功能	血漿蛋白結合; cyclin-dependent protein serine/threonine kinase inhibitor activity; protein kinase binding;
細胞組分	細胞質; 細胞質基質; 細胞核;
生物學過程	細胞週期; regulation of cyclin-dependent protein serine/threonine kinase activity; oligodendrocyte differentiation; negative regulation of phosphorylation; negative regulation of cell growth; negative regulation of cell population proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; G1/S transition of mitotic cell cycle; negative regulation of G1/S transition of mitotic cell cycle;
	來源：Amigo / QuickGO
直系同源
	1031
	12580
	ENSG00000123080
	ENSMUSG00000028551
	P42773
	Q60772
	NM_078626; NM_001262
	NM_001301368; NM_007671
	NP_001253; NP_523240
	NP_001288297; NP_031697
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CDKN2C，全稱週期素依賴性激酶4抑制蛋白C（英語：Cyclin-dependent kinase 4 inhibitor C），也稱為p18蛋白，由人類基因 CDKN2C編碼，是週期素依賴性激酶抑制蛋白 INK4家族的一員^[5]^[6]^[7]。

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000123080 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000028551 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Guan, K L; Jenkins, C W; Li, Y; Nichols, M A; Wu, X; O'Keefe, C L; Matera, A G; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.. Genes & Development. 1994-12-15, 8 (24). ISSN 0890-9369. doi:10.1101/gad.8.24.2939 （英語）.
^ Blais, Alexandre; Labrie, Yvan; Pouliot, Frédéric; Lachance, Yves; Labrie, Claude. Structure of the Gene Encoding the Human Cyclin-Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer. Biochemical and Biophysical Research Communications. 1998-06-09, 247 (1). ISSN 0006-291X. doi:10.1006/bbrc.1998.8497 （英語）.
^ Entrez Gene: CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). [2021-08-23]. （原始內容存檔於2010-12-05）.

外部連結

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000123080 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000028551 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8001816-5] Guan, K L; Jenkins, C W; Li, Y; Nichols, M A; Wu, X; O'Keefe, C L; Matera, A G; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.. Genes & Development. 1994-12-15, 8 (24). ISSN 0890-9369. doi:10.1101/gad.8.24.2939 （英語）.

[pmid9636670-6] Blais, Alexandre; Labrie, Yvan; Pouliot, Frédéric; Lachance, Yves; Labrie, Claude. Structure of the Gene Encoding the Human Cyclin-Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer. Biochemical and Biophysical Research Communications. 1998-06-09, 247 (1). ISSN 0006-291X. doi:10.1006/bbrc.1998.8497 （英語）.

[entrez-7] Entrez Gene: CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). [2021-08-23]. （原始內容存檔於2010-12-05）.

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