McN-481
| McN-481[1] | |
|---|---|
| |
| 別名 | McNeil 481 NSC-42268 13M2B[2] |
| 識別 | |
| CAS號 | 3625-18-1 |
| PubChem | 19251 |
| ChemSpider | 18164 |
| SMILES |
|
| 性質 | |
| 化學式 | C12H18N2O3 |
| 摩爾質量 | 238.28 g·mol−1 |
| 危險性 | |
| 致死量或濃度： | |
LD50（中位劑量）
|
3.5 mg/kg (mice, intraperitoneal)[3] |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
McN-481是一種含氮有機化合物，分子式C
12H
18N
2O
3，是5-(1,3-二甲基丁基)-5-乙基巴比妥酸（DMBB）的脫氫衍生物，能作為巴比妥類驚厥劑[3][4]。
參考文獻
[編輯]- ^ Brown, DA; Quilliam, JP. The effects of some centrally acting drugs on ganglionic transmission in the cat.. British Journal of Pharmacology and Chemotherapy. October 1964, 23 (2): 241–56. PMC 1704089
. PMID 19108183. doi:10.1111/j.1476-5381.1964.tb01583.x.
- ^ Jones, G. P.; Horn, E. Conformations of barbiturates related to pentobarbitone. IV. Crystal structure of 5-ethyl,5-(1?,3?-dimethylbut-2?-enyl) barbituric acid. Journal of Crystallographic and Spectroscopic Research. October 1986, 16 (5): 629–637. Bibcode:1986JCCry..16..629J. doi:10.1007/BF01181245.
- ^ 3.0 3.1 Cain, C. K.; Kleis, John. 5-Ethyl-5-(1,3-Dimethyi-2-Butenyl)Barbituric Acid, A Potent Central Nervous System Stimulant. Journal of Medicinal and Pharmaceutical Chemistry. February 1959, 1 (1): 31–36. PMID 13655027. doi:10.1021/jm50002a003.
- ^ Barbituric acid product. 26 March 1957.
