P-7521

P-7521
識別資訊
	IUPAC命名法 3-[9-methoxy-3-(2-phenylethyl)-3-azabicyclo[3.3.1]nonan-9-yl]phenol; ;
CAS號	92836-37-8
PubChem CID	146384;
ChemSpider	129116;
CompTox Dashboard (EPA)	DTXSID60918935 ;
化學資訊
化學式	C23H29NO2
摩爾質量	351.49 g·mol−1
3D模型（JSmol）	交互式圖像;
	SMILES COC1(C2CCCC1CN(C2)CCC3=CC=CC=C3)C4=CC(=CC=C4)O;
	InChI InChI=1S/C23H29NO2/c1-26-23(19-9-6-12-22(25)15-19)20-10-5-11-21(23)17-24(16-20)14-13-18-7-3-2-4-8-18/h2-4,6-9,12,15,20-21,25H,5,10-11,13-14,16-17H2,1H3; Key:UXFOUDJIDGKJDT-UHFFFAOYSA-N;

P-7521（化學名：3-(β-苯乙基)-9β-甲氧基-9α-(間-羥苯基)-3-氮雜二環[3,3,1]-壬烷，英語：3-(β-phenylethyl)-9β-methoxy-9α-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane）是一種含氮有機化合物，化學式C
23H
29NO
2，1980年代在中國研發，能作為阿片類止痛藥^[1]^[2]^[3]^[4]。

另見

非那佐辛

參考文獻

^ Zhou J, Zheng WJ, Chi ZQ. [Analgesic activity and respiratory inhibition of 3-beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane (P-7521) in rabbits]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. January 1987, 8 (1): 10–13. PMID 2955652.
^ Zhou DH, Ge BL, Xu XJ, Chi ZQ. [Effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (P-7521) on opiate receptor binding in vitro]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. November 1988, 9 (6): 511–515. PMID 2855686.
^ Jin WQ, Fan LQ, Chen XJ, Chi ZQ. P-7521--a new irreversible opioid ligand. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. May 1989, 10 (3): 205–210. PMID 2558497.
^ Chi ZQ, Jin WQ. A potent and long-lasting ligand, azabicyclononane (P-7521). Progress in Clinical and Biological Research. 1990, 328: 1–4. PMID 2154758.

[1] Zhou J, Zheng WJ, Chi ZQ. [Analgesic activity and respiratory inhibition of 3-beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane (P-7521) in rabbits]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. January 1987, 8 (1): 10–13. PMID 2955652.

[2] Zhou DH, Ge BL, Xu XJ, Chi ZQ. [Effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (P-7521) on opiate receptor binding in vitro]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. November 1988, 9 (6): 511–515. PMID 2855686.

[3] Jin WQ, Fan LQ, Chen XJ, Chi ZQ. P-7521--a new irreversible opioid ligand. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. May 1989, 10 (3): 205–210. PMID 2558497.

[4] Chi ZQ, Jin WQ. A potent and long-lasting ligand, azabicyclononane (P-7521). Progress in Clinical and Biological Research. 1990, 328: 1–4. PMID 2154758.

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