SNAPC4

SNAPC4
標識符
代號	SNAPC4
擴展標識	OMIM：602777；MGI：2443935；HomoloGene：2321；GeneCards：SNAPC4；OMA：SNAPC4 - orthologs
基因位置（人類） 染色體 9號染色體 基因座 9q34.3 起始 136,375,567 bp 終止 136,400,176 bp
基因位置（小鼠） 染色體 小鼠2號染色體 基因座 2|2 A3 起始 26,252,777 bp 終止 26,270,665 bp
RNA表達模式 Bgee 人類 小鼠（直系同源） Top expressed in right uterine tube paraflocculus of cerebellum right testis left testis right hemisphere of cerebellum frontal pole pancreatic ductal cell nasal epithelium Top expressed in neural layer of retina tail of embryo lumbar subsegment of spinal cord ventricular zone cerebellar cortex 查閱更多表達數據 BioGPS 查閱更多表達數據
基因本體 分子功能 DNA結合轉錄因子活性 DNA結合 sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific 細胞組分 細胞核 核質 snRNA-activating protein complex 生物學過程 regulation of transcription, DNA-templated transcription by RNA polymerase II transcription, DNA-templated snRNA transcription by RNA polymerase III transcription by RNA polymerase III regulation of transcription by RNA polymerase II snRNA transcription by RNA polymerase II 細胞分化 snRNA transcription 來源：Amigo / QuickGO
直系同源 物種 人類 小鼠 Entrez 6621 227644 Ensembl ENSG00000165684 ENSMUSG00000036281 UniProt Q5SXM2 Q8BP86 mRNA序列 NM_003086 ​NM_001394201 ​NM_001394202 ​NM_001394203 NM_001290419 ​NM_172339 蛋白序列 NP_003077 NP_001277348 ​NP_758842 ​NP_001393660 ​NP_001393661 ​NP_001393662 ​NP_001393663 ​NP_001393664 ​NP_001393665 ​NP_001393666 ​NP_001393667 ​NP_001393668 基因位置 Chr 9：136.38 – 136.4 Mb Chr 2：26.25 – 26.27 Mb PubMed查詢
維基數據
檢視/編輯人類 檢視/編輯小鼠

snRNA活化蛋白複合體第四亞基（英語：snRNA-activating protein complex subunit 4）是一個由人類基因 SNAPC4 編碼的蛋白質。化學式為：C₆₉₆₂H₁₁₂₀₃O₂₁₅₈N₂₀₇₅S₂₉

相互作用

SNAPC4能與SNAPC1、POU2F1和SNAPC2相互作用。

延伸閱讀

• Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995, 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0. 
• Ma B, Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. 2001, 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200. 
• Hovde S, Brooks A, Strong K, Geiger JH. Crystallization of the Oct-1/SNAP190 peptide/DNA complex. Acta Crystallogr. D Biol. Crystallogr. 2002, 58 (Pt 3): 511–2. PMID 11856838. doi:10.1107/S0907444901021461. 
• Strausberg RL; Feingold EA; Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899. 
• Hinkley CS; Hirsch HA; Gu L; et al. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J. Biol. Chem. 2003, 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200. 
• Ota T; Suzuki Y; Nishikawa T; et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. 2004, 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 
• Humphray SJ; Oliver K; Hunt AR; et al. DNA sequence and analysis of human chromosome 9. Nature. 2004, 429 (6990): 369–74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465. 
• Beausoleil SA; Jedrychowski M; Schwartz D; et al. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc. Natl. Acad. Sci. U.S.A. 2004, 101 (33): 12130–5. PMC 514446 . PMID 15302935. doi:10.1073/pnas.0404720101. 
• Gu L, Esselman WJ, Henry RW. Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC. J. Biol. Chem. 2005, 280 (30): 27697–704. PMID 15955816. doi:10.1074/jbc.M503206200. 
• Gu L, Husain-Ponnampalam R, Hoffmann-Benning S, Henry RW. The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III. J. Biol. Chem. 2007, 282 (38): 27887–96. PMID 17670747. doi:10.1074/jbc.M702269200.