MYO1C

MYO1C
已知的结构
PDB	直系同源搜索：PDBe RCSB
PDBID列表
	4BYF
标识符
代号	MYO1C
扩展标识	OMIM：606538；MGI：106612；HomoloGene：32046；GeneCards：MYO1C；OMA：MYO1C - orthologs
基因位置（人类）
染色体	17号染色体
终止	1,492,686 bp
基因位置（小鼠）
染色体	小鼠11号染色体
终止	75,564,736 bp
RNA表达模式
	Top expressed in
	right lung; ; subcutaneous adipose tissue; ; tibial arteries; ; buccal mucosa cell; ; abdominal fat;
	Top expressed in
	right lung; ; right lung lobe; ; left lung; ; tunica media of zone of aorta; ; left lung lobe; ; endothelial cell of lymphatic vessel;
	查阅更多表达数据
	; ;
	查阅更多表达数据
基因本体
分子功能	protein C-terminus binding; 核苷酸结合; actin binding; signaling receptor binding; cytoskeletal motor activity; calmodulin binding; ATP结合; 血浆蛋白结合; microfilament motor activity; actin filament binding; microtubule motor activity; microtubule binding;
细胞组分	外排体; filamentous actin; 刷状缘; 核仁; 细胞质; 核孔; cell projection; 细胞质基质; 细胞核; 应力纤维; stereocilium; unconventional myosin complex; 微绒毛; basal plasma membrane; 膜; myosin I complex; ruffle; 脂筏模型; 细胞膜; myosin complex; cytoplasmic vesicle; stereocilium membrane; lateral plasma membrane; ruffle membrane; 核质; nuclear body; stereocilium bundle; cytoplasmic vesicle membrane; phagocytic vesicle;
生物学过程	Fc-gamma receptor signaling pathway involved in phagocytosis; positive regulation of protein targeting to membrane; positive regulation of cell migration by vascular endothelial growth factor signaling pathway; epigenetic maintenance of chromatin in transcription-competent conformation; positive regulation of cell migration; 蛋白质导向; regulation of bicellular tight junction assembly; protein transport; protein targeting to membrane; mRNA transport; positive regulation of vascular endothelial growth factor signaling pathway; positive regulation of cellular response to insulin stimulus; positive regulation of actin filament polymerization; transport; vesicle transport along actin filament; cellular response to interferon-gamma; microtubule-based movement;
	来源：Amigo / QuickGO
直系同源
	4641
	17913
	ENSG00000197879
	ENSMUSG00000017774
	O00159
	Q9WTI7
	NM_033375; NM_001080779; NM_001080950; NM_001363855
	NM_001080774; NM_001080775; NM_008659; NM_001370611
	NP_001074248; NP_001074419; NP_203693; NP_001350784
	NP_001074243; NP_001074244; NP_032685; NP_001357540
	维基数据
查看/编辑人类	查看/编辑小鼠

MYO1C是一个位于人类17号染色体上的基因，编码一种隶属肌凝蛋白超家族的蛋白肌凝蛋白-Ic（Myosin-Ic）。MYO1C编码的肌凝蛋白-Ic是一种非典型的肌凝蛋白，与编码肌凝蛋白-1的MYH1是两种不同的基因。肌凝蛋白-Ic位于细胞质中，但肌凝蛋白-Ic的一种异构体位于细胞核中，与RNA聚合酶I（英语：RNA polymerase I）、RNA聚合酶Ⅱ引导的转录起始有关^[5]^[6]^[7]。

参见

肌凝蛋白

参考资料

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000197879 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000017774 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ MYO1C Gene. GeneCards. [2021-05-02]. （原始内容存档于2021-06-04）.
^ Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C. Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. Apr 1997, 40 (2): 332–41. PMID 9119401. doi:10.1006/geno.1996.4526.
^ Entrez Gene: MYO1C myosin IC. [2021-05-02]. （原始内容存档于2010-12-05）.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000197879 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000017774 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] MYO1C Gene. GeneCards. [2021-05-02]. （原始内容存档于2021-06-04）.

[pmid9119401-6] Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C. Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. Apr 1997, 40 (2): 332–41. PMID 9119401. doi:10.1006/geno.1996.4526.

[entrez-7] Entrez Gene: MYO1C myosin IC. [2021-05-02]. （原始内容存档于2010-12-05）.

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