YTHDF3

YTHDF3
標識符
代號	YTHDF3
擴展標識	MGI：1918850；HomoloGene：34991；GeneCards：YTHDF3；OMA：YTHDF3 - orthologs
基因位置（人類）
染色體	8號染色體
終止	63,212,786 bp
基因位置（小鼠）
染色體	小鼠3號染色體
終止	16,271,201 bp
RNA表現模式
	Top expressed in
	Epithelium of choroid plexus; ; Skeletal muscle tissue of biceps brachii; ; epithelium of nasopharynx; ; mucosa of paranasal sinus;
	Top expressed in
	conjunctival fornix; ; embryonic cell; ; tail of embryo; ; migratory enteric neural crest cell; ; cumulus cell;
	查閱更多表現資料
	; ;
	查閱更多表現資料
基因本體
分子功能	血漿蛋白結合; N6-methyladenosine-containing RNA binding; RNA binding; ribosome binding;
細胞組分	細胞質; 細胞質基質;
生物學過程	positive regulation of translation; positive regulation of translational initiation; mRNA destabilization;
	來源：Amigo / QuickGO
直系同源
	253943
	229096
	ENSG00000185728
	ENSMUSG00000047213
	Q7Z739
	Q8BYK6
NM_001277813; NM_001277814; NM_001277815; NM_001277816; NM_001277817;
	NM_001277818; NM_152758
	NM_001145919; NM_172677; NM_001358041; NM_001358042; NM_001358043
NP_001264742; NP_001264743; NP_001264744; NP_001264745; NP_001264746;
	NP_001264747; NP_689971
	NP_001139391; NP_766265; NP_001344970; NP_001344971; NP_001344972
	維基數據
檢視/編輯人類	檢視/編輯小鼠

YTHDF3是一個位於人類第8號染色體上的基因，編碼蛋白YTHDF3蛋白（YTHDF意為「YTH結構域家族」（英語：YTH domain family））。YTHDF3基因與YTHDF1屬旁系同源，編碼的YTHDF3蛋白功能可能是識別並結合N6-甲基腺苷（m⁶A）修飾的mRNA，並增加與之結合的mRNA易位效率^[5]^[6]^[7]。

參見

YTH結構域（英語：YTH protein domain）
N6-甲基腺苷（m⁶A）

參考資料

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000185728 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000047213 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ YTHDF3 Gene. GeneCards. [2021-05-03]. （原始內容存檔於2021-05-06）.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. Dec 2002, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
^ Entrez Gene: YTHDF3 YTH domain family, member 3. [2021-05-03]. （原始內容存檔於2010-12-05）.

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[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000185728 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000047213 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] YTHDF3 Gene. GeneCards. [2021-05-03]. （原始內容存檔於2021-05-06）.

[pmid12477932-6] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. Dec 2002, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.

[entrez-7] Entrez Gene: YTHDF3 YTH domain family, member 3. [2021-05-03]. （原始內容存檔於2010-12-05）.

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