HIST4H4

HIST4H4
已知的结构 PDB 直系同源搜索：PDBe RCSB PDBID列表 4H9O、3WKJ、3AYW、3WA9、5B0Z、5AVB、2CV5、5AV5、3AV2、3WTP、3AV1、3AZK、3X1V、5AV8、1F66、4QUU、3CFS、4YYK、4QUT、3NQJ、3A6N、3W99、5AVC、2RS9、3F9Z、3QZT、3QBY、3W97、4M38、4YM6、3CFV、4HGA、1EQZ、2RJE、3QZV、1HQ3、4H9P、3AZL、3AFA、1TZY、3UVY、5CPK、3JPX、4U9W、4N3W、4YYJ、4YYD、4H9N、4H9R、3AZI、4LD9、3UVX、3AZH、5BNX、4N4F、1U35、4YYG、3O36、2ARO、5AV9、4H9S、3AZF、3W98、4GQB、4H9Q、5BNV、3WAA、3AZG、3AZE、2RNY、1ZKK、2QQS、2LVM、3X1T、3AN2、2KWO、3QZS、3F9W、5FFW、5CPJ、3F9X、3IJ1、4YM5、3AZJ、4YY6、3AZN、2IG0、4YYH、4YYI、5CPI、3W96、3R45、2KWN、3F9Y、5AV6、3AZM、5BO0、3X1S、4QYD、4KGC、3UVW、4YYN、3X1U、3UW9、2F8N、3NQU、5B0Y、4YYM、5C3I、4Z5T、5B24、5FA5、4Z2M、5E5A、5FWE、5B2I、5B40、5B2J、5JA4、5AY8、4ZUX
标识符
代号	H4-16
扩展标识	OMIM：615069；MGI：2448432；HomoloGene：134468；GeneCards：H4-16；OMA：H4-16 - orthologs
基因位置（人类） 染色体 12號染色體 基因座 12p12.3 起始 14,767,999 bp 终止 14,771,131 bp
基因位置（小鼠） 染色体 小鼠13号染色体 基因座 13|13 A3.1 起始 22,224,806 bp 终止 22,225,532 bp
RNA表达模式 Bgee 人类 小鼠（直系同源） Top expressed in epithelium of colon right uterine tube body of pancreas Top expressed in muscle of thigh ventricular zone 查阅更多表达数据 BioGPS 无数据
基因本體 分子功能 protein domain specific binding 血浆蛋白结合 protein heterodimerization activity DNA结合 histone binding RNA binding 細胞組分 膜 染色体 核质 細胞外區域 nuclear chromosome 核小體 外排體 细胞核 细胞外间质 大分子复合体 生物學過程 telomere organization epigenetic maintenance of chromatin in transcription-competent conformation protein heterotetramerization negative regulation of megakaryocyte differentiation CENP-A containing chromatin assembly DNA replication-dependent chromatin assembly rDNA heterochromatin assembly negative regulation of gene expression, epigenetic DNA-templated transcription, initiation double-strand break repair via nonhomologous end joining beta-catenin-TCF complex assembly telomere capping nucleosome assembly regulation of gene silencing by miRNA regulation of megakaryocyte differentiation regulation of hematopoietic stem cell differentiation 来源：Amigo / QuickGO
直系同源 物種 人類 小鼠 Entrez 121504 319158 Ensembl ENSG00000197837 ENSMUSG00000060639 UniProt P62805 P62806 mRNA序列 NM_175054 NM_175656 蛋白序列 NP_003537 ​NP_003486 ​NP_003535 ​NP_003539 ​NP_003531 ​NP_003536 NP_291074 ​NP_783587 ​NP_783588 ​NP_835499 ​NP_835500 ​NP_001182350 ​NP_835515 ​NP_783585 ​NP_783586 ​NP_835582 ​NP_835583 ​NP_783583 ​NP_694813 基因位置 Chr 12：14.77 – 14.77 Mb Chr 13：22.22 – 22.23 Mb PubMed查询
维基数据
檢視/編輯人類 檢視/編輯小鼠

HIST4H4爲人體中的一種編碼一類組蛋白H4的基因，化学式为C₄₉₄H₈₃₇N₁₆₃O₁₃₄S。HIST4H4沒有內含子，編碼組蛋白H4家族中的一種蛋白質。HIST4H4基因對應的mRNA缺乏Poly(A)尾巴。不過，這類mRNA有一個回文終止元件。

拓展閱讀

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