CRLF2

CRLF2
已知的結構
PDB	直系同源搜尋：PDBe RCSB
PDBID列表
	4NN5、4NN6、4NN7
標識符
代號	CRLF2
擴展標識	OMIM：300357, 400023；MGI：1889506；HomoloGene：49476；GeneCards：CRLF2；OMA：CRLF2 - orthologs
基因位置（人類）
染色體	X染色體
終止	1,212,723 bp
基因位置（小鼠）
染色體	小鼠5號染色體
終止	109,706,859 bp
RNA表達模式
	Top expressed in
	palpebral conjunctiva; ; right lung; ; upper lobe of left lung;
	Top expressed in
	stroma of bone marrow; ; subcutaneous adipose tissue; ; barrel cortex; ; tunica media of zone of aorta;
	查閱更多表達數據
	無數據
基因本體
分子功能	cytokine receptor activity; cytokine binding;
細胞組分	膜; integral component of membrane; 細胞外區域; 細胞膜; external side of plasma membrane; receptor complex;
生物學過程	interleukin-7-mediated signaling pathway; positive regulation of cell population proliferation; cytokine-mediated signaling pathway; positive regulation of mast cell activation; positive regulation of receptor signaling pathway via STAT;
	來源：Amigo / QuickGO
直系同源
	64109
	57914
	ENSG00000205755
	ENSMUSG00000033467
	Q9HC73
	Q8CII9
	NM_001012288; NM_022148
	NM_001164735; NM_016715; NM_001310694
	NP_001012288; NP_071431
	NP_001158207; NP_001297623; NP_057924
	維基數據
檢視/編輯人類	檢視/編輯小鼠

CRLF2（英語：Cytokine receptor-like factor 2，細胞因子受體樣因子2，也稱為TSLP-R，TSLP受體，Thymic stromal lymphopoietin receptor）是一種由人類基因 CRLF2 編碼的蛋白質^[5]，與白介素-7受體α亞基（IL-7Ra）共同構成胸腺基質淋巴細胞生成素（TSLP）的受體^[6]。

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000205755 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033467 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: CRLF2 cytokine receptor-like factor 2.
^ Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. Mar 2001, 281 (4): 878–83. PMID 11237741. doi:10.1006/bbrc.2001.4432.

外部連結

Human CRLF2 genome location and CRLF2 gene details page in the UCSC Genome Browser（英語：UCSC Genome Browser）.

這是一篇蛋白相關小作品。您可以透過編輯或修訂擴充其內容。

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000205755 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033467 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Entrez Gene: CRLF2 cytokine receptor-like factor 2.

[pmid11237741-6] Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. Mar 2001, 281 (4): 878–83. PMID 11237741. doi:10.1006/bbrc.2001.4432.

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