CRLF2

CRLF2
已知的结构
PDB	直系同源搜索：PDBe RCSB
PDBID列表
	4NN5、4NN6、4NN7
标识符
代号	CRLF2
扩展标识	OMIM：300357, 400023；MGI：1889506；HomoloGene：49476；GeneCards：CRLF2；OMA：CRLF2 - orthologs
基因位置（人类）
染色体	X染色体
终止	1,212,723 bp
基因位置（小鼠）
染色体	小鼠5号染色体
终止	109,706,859 bp
RNA表达模式
	Top expressed in
	palpebral conjunctiva; ; right lung; ; upper lobe of left lung;
	Top expressed in
	stroma of bone marrow; ; subcutaneous adipose tissue; ; barrel cortex; ; tunica media of zone of aorta;
	查阅更多表达数据
	无数据
基因本体
分子功能	cytokine receptor activity; cytokine binding;
细胞组分	膜; integral component of membrane; 细胞外区域; 细胞膜; external side of plasma membrane; receptor complex;
生物学过程	interleukin-7-mediated signaling pathway; positive regulation of cell population proliferation; cytokine-mediated signaling pathway; positive regulation of mast cell activation; positive regulation of receptor signaling pathway via STAT;
	来源：Amigo / QuickGO
直系同源
	64109
	57914
	ENSG00000205755
	ENSMUSG00000033467
	Q9HC73
	Q8CII9
	NM_001012288; NM_022148
	NM_001164735; NM_016715; NM_001310694
	NP_001012288; NP_071431
	NP_001158207; NP_001297623; NP_057924
	维基数据
查看/编辑人类	查看/编辑小鼠

CRLF2（英语：Cytokine receptor-like factor 2，细胞因子受体样因子2，也称为TSLP-R，TSLP受体，Thymic stromal lymphopoietin receptor）是一种由人类基因 CRLF2 编码的蛋白质^[5]，与白介素-7受体α亚基（IL-7Ra）共同构成胸腺基质淋巴细胞生成素（TSLP）的受体^[6]。

参考文献

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000205755 – Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033467 – Ensembl, 2017年5月
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: CRLF2 cytokine receptor-like factor 2.
^ Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. Mar 2001, 281 (4): 878–83. PMID 11237741. doi:10.1006/bbrc.2001.4432.

外部链接

Human CRLF2 genome location and CRLF2 gene details page in the UCSC Genome Browser（英语：UCSC Genome Browser）.

这是一篇蛋白相关小作品。您可以通过编辑或修订扩充其内容。

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000205755 – Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000033467 – Ensembl, 2017年5月

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Entrez Gene: CRLF2 cytokine receptor-like factor 2.

[pmid11237741-6] Zhang W, Wang J, Wang Q, Chen G, Zhang J, Chen T, Wan T, Zhang Y, Cao X. Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes. Biochem Biophys Res Commun. Mar 2001, 281 (4): 878–83. PMID 11237741. doi:10.1006/bbrc.2001.4432.

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