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IL2RA

本页使用了标题或全文手工转换
维基百科,自由的百科全书
(重定向自CD25
IL2RA
已知的结构
PDB直系同源搜索:PDBe RCSB
标识符
代号IL2RA
扩展标识OMIM147730MGI96549HomoloGene360GeneCardsIL2RAOMAIL2RA - orthologs
直系同源
物種人類小鼠
Entrez
3559
16184
Ensembl
ENSG00000134460
ENSMUSG00000026770
UniProt
P01589
P01590
mRNA序列
NM_000417
​NM_001308242
​NM_001308243
NM_008367
蛋白序列
NP_000408
​NP_001295171
​NP_001295172
NP_032393
基因位置Chr 10:6.01 – 6.06 MbChr 2:11.65 – 11.7 Mb
PubMed查询[3][4]
维基数据
檢視/編輯人類檢視/編輯小鼠

白介素-2受体α亚基(Interleukin-2 receptor subunit alpha,缩写IL2RA)也称为Tac抗原(Tac antigen)、P55、分化簇25CD25,cluster of differentiation 25)是一种细胞表面蛋白质,由人类基因 IL2RA 编码[5],与β亚基(CD122)、γ亚基(CD132)共同组成白介素-2受体[6]

参考资料

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  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000134460Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000026770Ensembl, 2017年5月
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Spolski R, Li P, Leonard WJ. Biology and regulation of IL-2: from molecular mechanisms to human therapy. Nature Reviews. Immunology. October 2018, 18 (10): 648–659. PMID 30089912. S2CID 51939991. doi:10.1038/s41577-018-0046-y. 
  6. ^ Zhou P. Emerging mechanisms and applications of low-dose IL-2 therapy in autoimmunity. Cytokine & Growth Factor Reviews. October 2022, 67: 80–88. PMID 35803833. S2CID 250200065. doi:10.1016/j.cytogfr.2022.06.003. 

外部链接

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