CYP2B6

Cytochrome P450, family 2, subfamily B, polypeptide 6
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 3IBD​, 3QOA​, 3QU8​, 3UA5​, 4I91​, 4RQL​, 4RRT​
标识
代号	CYP2B6; CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
扩展标识	遗传学：123930 鼠基因：88598 同源基因：73894 IUPHAR:   ChEMBL: 4729 GeneCards: CYP2B6 Gene
EC編號	1.14.14.1
基因本体论描述 分子功能 · monooxygenase activity · iron ion binding · arachidonic acid epoxygenase activity · steroid hydroxylase activity · oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen · oxygen binding · heme binding 细胞成分 · cytoplasm · endoplasmic reticulum membrane · intracellular membrane-bounded organelle 生物过程 · xenobiotic metabolic process · steroid metabolic process · drug metabolic process · epoxygenase P450 pathway · cellular ketone metabolic process · exogenous drug catabolic process · small molecule metabolic process · oxidation-reduction process Sources: Amigo / QuickGO
直系同源体
物种	人类	小鼠
Entrez	1555	13088
Ensembl	ENSG00000197408	ENSMUSG00000030483
UniProt	P20813	Q9WUD0
mRNA序列	NM_000767	NM_009999
蛋白序列	NP_000758	NP_034129
基因位置	Chr 19: 40.99 – 41.02 Mb	Chr 7: 25.9 – 25.93 Mb
PubMed查询	[1]	[2]

细胞色素P450 2B6（英語：Cytochrome P450 2B6），化学式为：C₂₆₁₂H₄₀₃₁O₇₀₂N₆₈₅S₁₈Fe，是一种由人类CYP2B6基因编码的酶。CYP2B6是细胞色素P450酶家族的一员。与CYP2A6一样，CYP2B6参与尼古丁等许多物质的代谢。