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CD132

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維基百科,自由的百科全書
CD132
已知的結構
PDB直系同源搜索:PDBe RCSB
標識符
代號IL2RG
擴展標識OMIM308380MGI96551HomoloGene172GeneCardsIL2RGOMAIL2RG - orthologs
直系同源
物種人類小鼠
Entrez
3561
16186
Ensembl
ENSG00000147168
ENSMUSG00000031304
UniProt
P31785
P34902
mRNA序列
NM_000206
NM_013563
​NM_001308535
蛋白序列
NP_000197
NP_001295464
​NP_038591
基因位置Chr X:71.11 – 71.11 MbChr X:100.31 – 100.31 Mb
PubMed查詢[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

CD132,又稱為共用γ鏈Common gamma chain,縮寫γc)化學式為:C2394H3675O956N525S15[5],白介素2受體γ亞基(interleukin-2 receptor subunit gamma,縮寫IL-2RG)是一種細胞因子受體亞基,存在於至少六種不同的白介素受體中:包括IL-2IL-4[6]IL-7[7]IL-9IL-15[8]IL-21的受體。γcI型細胞因子受體家族中的一種醣蛋白,表達於大部分的淋巴細胞群體,哺乳動物的此基因位於X染色體

參考文獻

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  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000147168Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000031304Ensembl, 2017年5月
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Expasy - ProtParam. web.expasy.org. [2026-01-26]. 
  6. ^ Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajima A, Puri RK, Paul WE. Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science. December 1993, 262 (5141): 1880–3. PMID 8266078. doi:10.1126/science.8266078. 
  7. ^ Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science. December 1993, 262 (5141): 1877–80. PMID 8266077. doi:10.1126/science.8266077. 
  8. ^ Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBose R, Cosman D, Park LS, Anderson DM. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. August 1995, 14 (15): 3654–63. PMC 394440可免費查閱. PMID 7641685. 

延伸閱讀

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外部連結

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