CD132

CD132
已知的结构 PDB 直系同源搜索：PDBe RCSB PDBID列表 2B5I、2ERJ、3BPL、3QAZ、3QB7、4GS7
标识符
代号	IL2RG
扩展标识	OMIM：308380；MGI：96551；HomoloGene：172；GeneCards：IL2RG；OMA：IL2RG - orthologs
基因位置（人类） 染色体 X染色體 基因座 Xq13.1 起始 71,107,404 bp 终止 71,112,108 bp
基因位置（小鼠） 染色体 小鼠X染色体 基因座 X D|X 43.9 cM 起始 100,307,984 bp 终止 100,311,861 bp
RNA表达模式 Bgee 人类 小鼠（直系同源） Top expressed in mucosa of ileum jejunal mucosa Top expressed in right lung right lung lobe subcutaneous adipose tissue left lung 查阅更多表达数据 BioGPS 查阅更多表达数据
基因本體 分子功能 interleukin-7 receptor activity interleukin-2 receptor activity 血浆蛋白结合 cytokine receptor activity interleukin-4 receptor activity interleukin-2 binding cytokine binding interleukin-15 receptor activity 細胞組分 integral component of membrane 膜 细胞膜 integral component of plasma membrane external side of plasma membrane 核内体 细胞质基质 cell surface receptor complex 生物學過程 MAPK cascade 免疫反应 viral process 訊息傳遞 interleukin-2-mediated signaling pathway interleukin-4-mediated signaling pathway interleukin-7-mediated signaling pathway interleukin-15-mediated signaling pathway interleukin-9-mediated signaling pathway 分子功能调控 cytokine-mediated signaling pathway interleukin-21-mediated signaling pathway positive regulation of phagocytosis 来源：Amigo / QuickGO
直系同源 物種 人類 小鼠 Entrez 3561 16186 Ensembl ENSG00000147168 ENSMUSG00000031304 UniProt P31785 P34902 mRNA序列 NM_000206 NM_013563 ​NM_001308535 蛋白序列 NP_000197 NP_001295464 ​NP_038591 基因位置 Chr X：71.11 – 71.11 Mb Chr X：100.31 – 100.31 Mb PubMed查询
维基数据
檢視/編輯人類 檢視/編輯小鼠

CD132，又称为共用γ链（Common gamma chain，缩写γ_c)化学式为：C₂₃₉₄H₃₆₇₅O₉₅₆N₅₂₅S₁₅，白介素2受体γ亚基（interleukin-2 receptor subunit gamma，缩写IL-2RG）是一种细胞因子受体亚基，存在于至少六种不同的白介素受体中：包括IL-2、IL-4、IL-7、IL-9、IL-15和IL-21的受体。γ_c是I型细胞因子受体家族中的一种醣蛋白，表达于大部分的淋巴细胞群体，哺乳动物的此基因位于X染色体。

延伸阅读

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外部链接

• 醫學主題詞表（MeSH）：Interleukin+Receptor+Common+gamma+Subunit